Concepedia

Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: design, conformation and conversion to α-ketoamide inhibitors

Gordon Bruton, Anthony Huxley, Peter J. O’Hanlon, Barry S. Orlek, Drake S. Eggleston, John Eric Humphries, Simon A. Readshaw, Andrew B. West, Stephen Ashman, Murray J. B. Brown,

European Journal of Medicinal Chemistry · 2003 · 52 citations · 7 references

DOI

Concepts

References

7

Patterns of Amino Acids near Signal‐Sequence Cleavage Sites

Gunnar von Heijne · European Journal of Biochemistry · 1983 · 2.3K citations · Full text

Molecular cloning and expression of the spsB gene encoding an essential type I signal peptidase from Staphylococcus aureus

K M Cregg, I Wilding, M. BLACK · Journal of Bacteriology · 1996 · 110 citations · Full text

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Inhibitors of Bacterial Signal Peptidases

M. BLACK, Gordon Bruton · Current Pharmaceutical Design · 1970 · 65 citations

, , +21

Common protein architecture and binding sites in proteases utilizing a Ser/Lys dyad mechanism

Mark Paetzel, N.C.J. Strynadka · Protein Science · 1999 · 53 citations · Full text

Determination ofKm andkcat for Signal Peptidase I Using a Full Length Secretory Precursor, pro-OmpA-nuclease A<//INF><//INF>

Sukalyan Chatterjee, Dominic Suciu, Ross Dalbey et al. · Journal of Molecular Biology · 1995 · 44 citations

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