Harshad K. Rami

Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist

Martin J. Gunthorpe, Harshad K. Rami, Jeffrey C. Jerman et al. · Neuropharmacology · 2003 · 273 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development

Harshad K. Rami, Mervyn Thompson, Geoffrey Stemp et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 132 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +5

Characterization of SB-705498, a Potent and Selective Vanilloid Receptor-1 (VR1/TRPV1) Antagonist That Inhibits the Capsaicin-, Acid-, and Heat-Mediated Activation of the Receptor

Martin J. Gunthorpe, Sara Luis Hannan, Darren Smart et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 105 citations

Medicine, Medicinal Chemistry, Pharmacology +17

The contribution of classical (beta1/2-) and atypical beta-adrenoceptors to the stimulation of human white adipocyte lipolysis and right atrial appendage contraction by novel beta3-adrenoceptor agonists of differing selectivities.

Matthew V. Sennitt, Alberto J. Kaumann, Peter Molenaar et al. · PubMed · 1998 · 59 citations

Medicine, Endocrinology, Pharmacology +10

3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity

Peter J. Atkinson, Steven M. Bromidge, Mark Duxon et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 55 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9