C. Bountra

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Laurens Kruidenier, Chun‐wa Chung, Zhongjun Cheng et al. · Nature · 2012 · 958 citations · Full text

Life Sciences, Cell Biology, Immunology +14

The promise and peril of chemical probes

C.H. Arrowsmith, James E. Audia, Christopher P. Austin et al. · Nature Chemical Biology · 2015 · 850 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +12

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain

Iain P. Chessell, Jonathan P. Hatcher, C. Bountra et al. · Pain · 2005 · 784 citations

Life Sciences, Immunology, Neurobiology +17

COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord

Y. Yiangou, P. Facer, Pascal F. Durrenberger et al. · BMC Neurology · 2006 · 508 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain

S. Picaud, Christopher Wells, I. Felletar et al. · Proceedings of the National Academy of Sciences · 2013 · 481 citations · Full text

Life Sciences, Molecular Biology, Cell Signaling +11