I. Felletar

Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.2K citations · Full text

Bet Bromodomains, Genetics, Pathogenesis +3

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

P. Filippakopoulos, S. Picaud, Maria Mangos et al. · Cell · 2012 · 1.7K citations · Full text

Structural Bioinformatics, Epigenetic Change, Genetics +25

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain

S. Picaud, Christopher Wells, I. Felletar et al. · Proceedings of the National Academy of Sciences · 2013 · 475 citations · Full text

Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery

Martin Philpott, Jing Yang, Tony Tumber et al. · Molecular BioSystems · 2011 · 133 citations

Histone Modifications, Epigenetic Change, Molecular Biology +23

[1,2,4]Triazolo[4,3-<i>a</i>]phthalazines: Inhibitors of Diverse Bromodomains

O. Fedorov, Hannah Lingard, Christopher Wells et al. · Journal of Medicinal Chemistry · 2013 · 98 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Bet Bromodomains +13