Martin Philpott

Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +5

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain

S. Picaud, Christopher Wells, I. Felletar et al. · Proceedings of the National Academy of Sciences · 2013 · 481 citations · Full text

Life Sciences, Molecular Biology, Cell Signaling +11

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

Duncan A. Hay, Oleg Fedorov, Sarah Martin et al. · Journal of the American Chemical Society · 2014 · 285 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains

S. Picaud, David Da Costa, Angeliki Thanasopoulou et al. · Cancer Research · 2013 · 247 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

S. Picaud, O. Fedorov, Angeliki Thanasopoulou et al. · Cancer Research · 2015 · 230 citations · Full text

Medicine, Oncology, Pharmacology +13