Duncan A. Hay

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

Duncan A. Hay, Oleg Fedorov, Sarah Martin et al. · Journal of the American Chemical Society · 2014 · 281 citations · Full text

Combinatorial Chemistry, Molecular Biology, Lead Identification +19

CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses

Ariane Hammitzsch, C. Tallant, O. Fedorov et al. · Proceedings of the National Academy of Sciences · 2015 · 252 citations · Full text

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

S. Picaud, O. Fedorov, Angeliki Thanasopoulou et al. · Cancer Research · 2015 · 224 citations · Full text

A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction

Timothy P. C. Rooney, P. Filippakopoulos, O. Fedorov et al. · Angewandte Chemie International Edition · 2014 · 115 citations · Full text

Design and synthesis of potent and selective inhibitors of BRD7 and BRD9 bromodomains

Duncan A. Hay, Catherine Rogers, Oleg Fedorov et al. · MedChemComm · 2015 · 68 citations · Full text

Combinatorial Chemistry, Halogenation, Medicinal Chemistry +14