Concepedia
Statistics
Publications
9
Citations
580
H-Index
Active since
2014
Affiliations
University of Oxford(Current)
University of Cambridge
Genomics (United Kingdom)
Granta Design (United Kingdom)
Timothy P. C. Rooney is an author at University of Oxford specializing in biochemistry, natural sciences, and drug discovery.
Top concepts
MedicineBiochemistryDrug DiscoveryNatural SciencesMolecular BiologyPharmacologySmall MoleculesChemical BiologyMolecular DockingMolecular Recognition
Publications per year
2014–2024
Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains
Duncan A. Hay, Oleg Fedorov, Sarah Martin et al. · Journal of the American Chemical Society · 2014 · 281 citations · Full text
Combinatorial Chemistry, Molecular Biology, Lead Identification +19
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction
Timothy P. C. Rooney, P. Filippakopoulos, O. Fedorov et al. · Angewandte Chemie International Edition · 2014 · 115 citations · Full text
Systematic Investigation of the Permeability of Androgen Receptor PROTACs
Duncan E. Scott, Timothy P. C. Rooney, Elliott D. Bayle et al. · ACS Medicinal Chemistry Letters · 2020 · 67 citations · Full text
Androgen Receptor, Protein Assembly, Molecular Biology +16
Isoxazole‐Derived Amino Acids are Bromodomain‐Binding Acetyl‐Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3
Angelina R. Sekirnik, David S. Hewings, Natalie H. Theodoulou et al. · Angewandte Chemie International Edition · 2016 · 31 citations · Full text
Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain
Michael Brand, James Clayton, Mustafa Moroglu et al. · Journal of Medicinal Chemistry · 2021 · 26 citations · Full text
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