Concepedia

Timothy P. C. Rooney

TP

Statistics

Publications

9

Citations

603

H-Index

9

Active since

2014

Affiliations

University of Oxford(Current)

University of Cambridge

Genomics (United Kingdom)

Granta Design (United Kingdom)

Timothy P. C. Rooney is an author at University of Oxford specializing in ligand binding, pharmacology, and life sciences.

ORCID

Publications per year

2014–2024

9

Publications

9

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

Duncan A. Hay, Oleg Fedorov, Sarah Martin et al. · Journal of the American Chemical Society · 2014 · 285 citations · Full text

, , +17

A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction

Timothy P. C. Rooney, P. Filippakopoulos, O. Fedorov et al. · Angewandte Chemie International Edition · 2014 · 115 citations · Full text

, , +14

Systematic Investigation of the Permeability of Androgen Receptor PROTACs

Duncan E. Scott, Timothy P. C. Rooney, Elliott D. Bayle et al. · ACS Medicinal Chemistry Letters · 2020 · 75 citations · Full text

, , +17

Isoxazole‐Derived Amino Acids are Bromodomain‐Binding Acetyl‐Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3

Angelina R. Sekirnik, David S. Hewings, Natalie H. Theodoulou et al. · Angewandte Chemie International Edition · 2016 · 31 citations · Full text

, , +14

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain

Michael Brand, James Clayton, Mustafa Moroglu et al. · Journal of Medicinal Chemistry · 2021 · 26 citations · Full text

, , +5

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