Natalie H. Theodoulou

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

Natalie H. Theodoulou, Paul Bamborough, Andrew J. Bannister et al. · Journal of Medicinal Chemistry · 2015 · 229 citations · Full text

Chemical Biology, Chromatin, Molecular Characterization +14

Alkene <i>anti</i>-Dihydroxylation with Malonoyl Peroxides

Carla Alamillo‐Ferrer, Stuart C. Davidson, Michael J. Rawling et al. · Organic Letters · 2015 · 37 citations

Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains

Michael A. Clegg, Paul Bamborough, Chun‐wa Chung et al. · Journal of Medicinal Chemistry · 2020 · 33 citations · Full text

Isoxazole‐Derived Amino Acids are Bromodomain‐Binding Acetyl‐Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3

Angelina R. Sekirnik, David S. Hewings, Natalie H. Theodoulou et al. · Angewandte Chemie International Edition · 2016 · 31 citations · Full text

Design, Synthesis, and Characterization of I-BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate

P. G. Humphreys, Stephen J. Atkinson, Paul Bamborough et al. · Journal of Medicinal Chemistry · 2022 · 20 citations · Full text