Concepedia
Statistics
Publications
12
Citations
737
H-Index
Active since
2011
Affiliations
University of Oxford(Current)
Roche (Switzerland)
Mansfield University
Genomics (United Kingdom)
Oxford Research Group
David S. Hewings is an author at University of Oxford specializing in organic chemistry, natural sciences, and biochemistry.
Top concepts
Organic ChemistryBiochemistryNatural SciencesMedicinePharmacologyDrug DiscoveryBiomolecular EngineeringChemistryEngineeringChemical Biology
Publications per year
2011–2023
3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands
David S. Hewings, Minghua Wang, Martin Philpott et al. · Journal of Medicinal Chemistry · 2011 · 222 citations · Full text
Histone Modifications, Molecular Biology, Organic Chemistry +19
Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands
David S. Hewings, O. Fedorov, P. Filippakopoulos et al. · Journal of Medicinal Chemistry · 2013 · 138 citations · Full text
Chemoprevention Strategy, Organic Chemistry, Chemistry +16
Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes
David S. Hewings, Johanna Heideker, P. Taylur et al. · Nature Communications · 2018 · 86 citations · Full text
The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains
Duncan A. Hay, O. Fedorov, P. Filippakopoulos et al. · MedChemComm · 2012 · 66 citations · Full text
Combinatorial Chemistry, Medicinal Chemistry, Bet Bromodomains +14
Organocatalytic removal of formaldehyde adducts from RNA and DNA bases
Saswata Karmakar, Emily M. Harcourt, David S. Hewings et al. · Nature Chemistry · 2015 · 50 citations · Full text
Formaldehyde Adducts, Engineering, Aldehyde Dehydrogenase +4
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