A. Chaikuad

Copper is required for oncogenic BRAF signalling and tumorigenesis

Donita C. Brady, Matthew S. Crowe, Michelle L. Turski et al. · Nature · 2014 · 581 citations · Full text

Oncogenic Agent, Metalloprotein, Medicine +3

Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases

Peter Canning, C.D.O. Cooper, T. Krojer et al. · Journal of Biological Chemistry · 2013 · 288 citations · Full text

The ins and outs of selective kinase inhibitor development

Susanne Müller, A. Chaikuad, Nathanael S. Gray et al. · Nature Chemical Biology · 2015 · 283 citations

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +4

A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics

A. Chaikuad, Eliana MC Tacconi, J. Zimmer et al. · Nature Chemical Biology · 2014 · 237 citations · Full text

Molecular Pharmacology, Slow Binding Kinetics, Signal Transduction +12

A New Class of Small Molecule Inhibitor of BMP Signaling

C. Sanvitale, Georgina Kerr, A. Chaikuad et al. · PLoS ONE · 2013 · 237 citations · Full text

Sclerostin, Molecular Biology, Signaling Pathway +17