Laurens Kruidenier

Catalytic in vivo protein knockdown by small-molecule PROTACs

Daniel P. Bondeson, Alina Mares, Ian E. Smith et al. · Nature Chemical Biology · 2015 · 1.3K citations · Full text

Biochemistry, Protein Assembly, Natural Sciences +2

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Laurens Kruidenier, Chun‐wa Chung, Zhongjun Cheng et al. · Nature · 2012 · 932 citations · Full text

Inflammation, Cytokine, Inflammatory Disease +12

Intestinal oxidative damage in inflammatory bowel disease: semi‐quantification, localization, and association with mucosal antioxidants

Laurens Kruidenier, Ineke Kuiper, Cornelis Bhw Lamers et al. · The Journal of Pathology · 2003 · 392 citations

Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group

Mercedes Lobera, Kevin P. Madauss, Denise Teotico Pohlhaus et al. · Nature Chemical Biology · 2013 · 368 citations

Histone Modifications, Chromatin, Nonchelating Zinc-binding Group +9

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

Panagiotis Ntziachristos, Aristotelis Tsirigos, G. Grant Welstead et al. · Nature · 2014 · 368 citations · Full text

Histone Modifications, Chromatin, Tumor Biology +14