J. Howard Jones - Concepedia

Author

J. Howard Jones

Biogen (United States)

Also Known As

J. Howard Jones, J.H. Jones, John H. Jones, John Howard Jones, Jones, John Howard, 1939-

Publications

452

Citations

H-Index

Concepts

All Affiliations

Biogen (United States)

About

J. Howard Jones is an author at Biogen (United States) specializing in medicine, cell signaling, and necroptosis.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	2	2	79
2	Natural Sciences	1	1	37
3	Biochemistry	1	1	37
4	Cell Biology	1	1	37
5	Chemistry	1	1	42

J. Howard Jones

Publications

448

Citations

H-Index

Page 1

	Year	Citations
Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-<i>N</i>-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications M.C. Van Zandt, Michael L. Jones, David Gunn, Journal of Medicinal Chemistry	2005	222
Design, synthesis and identification of novel, orally bioavailable non-covalent Nrf2 activators Bin Ma, Brian S. Lucas, Andrew G. Capacci, Bioorganic & Medicinal Chemistry Letters MedicineChemistryPharmacologyPharmaceutical ChemistryDrug Discovery	2019	42
ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis Bin Ma, Doug Marcotte, Murugan Paramasivam, PLoS ONE MitophagyApoptosisCell DeathCpd 1Receptor Tyrosine Kinase	2016	37
Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors Martin Himmelbauer, Zhili Xin, J. Howard Jones, Journal of Medicinal Chemistry	2019	34
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo Tamara Halkina, Jaclyn L. Henderson, Edward Yin-Shiang Lin, Journal of Medicinal Chemistry	2021	32
Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand D.J. Marcotte, Yuting Liu, Kevin Little, BMC Structural Biology	2016	31
Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors Zhili Xin, Martin Himmelbauer, J. Howard Jones, ACS Medicinal Chemistry Letters	2020	22
Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation <i>In Vivo</i> J. Howard Jones, Zhili Xin, Martin Himmelbauer, Journal of Medicinal Chemistry	2021	14
Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis Martin Himmelbauer, Bekim Bajrami, Rebecca Basile, Journal of Medicinal Chemistry	2024	14

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