David Gunn

Novel 3-Pyridyl Ethers with Subnanomolar Affinity for Central Neuronal Nicotinic Acetylcholine Receptors

Melwyn A. Abreo, Nan‐Horng Lin, David S. Garvey et al. · Journal of Medicinal Chemistry · 1996 · 231 citations

Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-<i>N</i>-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications

M.C. Van Zandt, Michael L. Jones, David Gunn et al. · Journal of Medicinal Chemistry · 2005 · 222 citations · Full text

Application of the Pummerer Reaction Toward the Synthesis of Complex Carbocycles and Heterocycles

Albert Padwa, David Gunn, Martin H. Osterhout · Synthesis · 1997 · 139 citations

Complex Carbocycles, Thionium Ions, Chemical Engineering +15

ABT-089 [2-Methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A Potent and Selective Cholinergic Channel Modulator with Neuroprotective Properties

James P. Sullivan, Diana L. Donnelly‐Roberts, Clark A. Briggs et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 78 citations

Structure−Activity Studies on 2-Methyl-3-(2(<i>S</i>)-pyrrolidinylmethoxy)pyridine (ABT-089):  An Orally Bioavailable 3-Pyridyl Ether Nicotinic Acetylcholine Receptor Ligand with Cognition-Enhancing Properties

Nan‐Horng Lin, David Gunn, Keith B. Ryther et al. · Journal of Medicinal Chemistry · 1997 · 67 citations · Full text

Favorable Oral Bioavailability, Neurotransmitter, Social Sciences +17