Keith B. Ryther

Functional Characterization of the Novel Neuronal Nicotinic Acetylcholine Receptor Ligand GTS-21 In Vitro and In Vivo

Clark A. Briggs, David J. Anderson, Jorge D. Brioni et al. · Pharmacology Biochemistry and Behavior · 1997 · 192 citations

Medicine, Nicotine, Receptor (Biochemistry) +6

Identification and Initial Structure−Activity Relationships of (<i>R</i>)-5-(2-Azetidinylmethoxy)-2-chloropyridine (ABT-594), a Potent, Orally Active, Non-Opiate Analgesic Agent Acting via Neuronal Nicotinic Acetylcholine Receptors

Mark W. Holladay, James T. Wasicak, Nan‐Horng Lin et al. · Journal of Medicinal Chemistry · 1998 · 131 citations · Full text

Pain Medicine, Neuropathic Pain, Orally Active +21

Characterization of a Cannabinoid CB2 Receptor-Selective Agonist, A-836339 [2,2,3,3-Tetramethyl-cyclopropanecarboxylic Acid [3-(2-Methoxy-ethyl)-4,5-dimethyl-3 H-thiazol-(2 Z)-ylidene]-amide], Using in Vitro Pharmacological Assays, in Vivo Pain Models, and Pharmacological Magnetic Resonance Imaging

Betty Yao, Gin C. Hsieh, A.V. Daza et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 91 citations

ABT-089 [2-Methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A Potent and Selective Cholinergic Channel Modulator with Neuroprotective Properties

James P. Sullivan, Diana L. Donnelly‐Roberts, Clark A. Briggs et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 78 citations

Structure−Activity Studies on 2-Methyl-3-(2(<i>S</i>)-pyrrolidinylmethoxy)pyridine (ABT-089):  An Orally Bioavailable 3-Pyridyl Ether Nicotinic Acetylcholine Receptor Ligand with Cognition-Enhancing Properties

Nan‐Horng Lin, David Gunn, Keith B. Ryther et al. · Journal of Medicinal Chemistry · 1997 · 67 citations · Full text

Favorable Oral Bioavailability, Neurotransmitter, Social Sciences +17