Concepedia

Functional Characterization of the Novel Neuronal Nicotinic Acetylcholine Receptor Ligand GTS-21 In Vitro and In Vivo

Clark A. Briggs, David J. Anderson, Jorge D. Brioni, Jerry J. Buccafusco, Michael Buckley, Jeffrey E. Campbell, Michael Decker, Diana L. Donnelly‐Roberts, Richard L. Elliott, Murali Gopalakrishnan,

Pharmacology Biochemistry and Behavior · 1997 · 192 citations · 37 references

DOI

Concepts

References

37

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

, , +9

Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

Peter J. Whitehouse, Donald L. Price, Arthur W. Clark et al. · Annals of Neurology · 1981 · 1.7K citations

, , +17

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment.

C M Flores, S W Rogers, L A Pabreza et al. · Molecular Pharmacology · 1992 · 875 citations

, , +17

The Binding of Agonists to Brain Muscarinic Receptors

N.J.M. Birdsall, A. S. V. Burgen, Edward C. Hulme · Molecular Pharmacology · 1978 · 676 citations

, , +17