Concepedia

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff

Biochemical Pharmacology · 1973 · 12.9K citations · 12 references

DOI

Concepts

References

12

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆I. Nomenclature and rate equations

W. W. Cleland · Biochimica et Biophysica Acta · 1963 · 2.1K citations

, , +16

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

W. W. Cleland · Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects · 1963 · 1.9K citations

, , +14

The Biochemistry of Folic Acid and Related Pteridines.

Annals of Internal Medicine · 1970 · 1K citations

, , +14

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆II. Inhibition: Nomenclature and theory

W. W. Cleland · Biochimica et Biophysica Acta · 1963 · 868 citations

, , +14

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

W. W. Cleland · Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects · 1963 · 854 citations

, , +14