Concepedia

Concentration-effect Relationships

Concentration-Effect Relationships is a pharmacological principle that describes the quantitative association between the concentration of a drug at its site of action and the magnitude of the resulting biological response.

1.5K

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109.6K

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4.4K

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1.2K

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2017–2026

93

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Concentration-response Relationships

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Publications

1.5K

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

Ting‐Chao Chou, Paul Talalay · Advances in Enzyme Regulation · 1984 · 7.2K citations

, , +16

Determination of minimum inhibitory concentrations

Jennifer M. Andrews · Journal of Antimicrobial Chemotherapy · 2001 · 4.1K citations · Full text

, , +6

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

O. ARUNLAKSHANA, H. O. Schild · British Journal of Pharmacology and Chemotherapy · 1959 · 4K citations · Full text

, , +16

THE TOXICITY OF POISONS APPLIED JOINTLY1

C. I. Bliss · Annals of Applied Biology · 1939 · 2.4K citations

, , +15

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Authors

4.4K

  1. MD
    Meindert Danhof

    Leiden University, Netherlands

    11 publications · 420 citations

    10

    h-index

  2. RJ
    Ronald J. Tallarida

    Temple University, United States

    8 publications · 881 citations

    8

    h-index

  3. RA
    Richard A. Meisch

    University of Minnesota, United States

    8 publications · 310 citations

    8

    h-index

  4. DA
    David Attwood

    University of Manchester, United Kingdom

    8 publications · 226 citations

    8

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  5. GL
    Gerhard Levy

    University at Buffalo, State University of New York, United States

    7 publications · 451 citations

    7

    h-index

1–5 of 4.4K

Institutions

1.2K

  1. University at Buffalo, State University of New York

    Buffalo, United States

    19 h-index

    60 publications

    6.8K citations

  2. Johns Hopkins University

    Baltimore, United States

    15 h-index

    78 publications

    15.2K citations

  3. University College London

    London, United Kingdom

    14 h-index

    30 publications

    10K citations

  4. National Institutes of Health

    Bethesda, United States

    13 h-index

    24 publications

    1.1K citations

  5. Johns Hopkins Medicine

    Baltimore, United States

    13 h-index

    45 publications

    12.8K citations

  6. Karolinska Institutet

    Stockholm, Sweden

    13 h-index

    34 publications

    994 citations

  7. Leiden University

    Leiden, The Netherlands

    13 h-index

    37 publications

    1.2K citations

  8. University of Minnesota

    Minneapolis, United States

    12 h-index

    23 publications

    906 citations

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Venues

  1. 32

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  2. Clinical Pharmacology & Therapeutics

    CPT · 42 publications · 2.5K citations

    26

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  3. PubMed

    Repository · 80 publications · 2.9K citations

    26

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  4. Psychopharmacology

    39 publications · 1.9K citations

    25

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  5. Biochemistry

    29 publications · 2K citations

    23

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