M.C. Van Zandt

Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-<i>N</i>-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications

M.C. Van Zandt, Michael L. Jones, David Gunn et al. · Journal of Medicinal Chemistry · 2005 · 222 citations · Full text

Discovery of (<i>R</i>)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury

M.C. Van Zandt, Darren L. Whitehouse, Adam Gołȩbiowski et al. · Journal of Medicinal Chemistry · 2013 · 84 citations · Full text

Lead Compounds, Pharmaceutical Science, Cardiovascular Pharmacology +19

Small molecules that target group II introns are potent antifungal agents

Olga Fedorova, G. Erik Jagdmann, Rebecca L. Adams et al. · Nature Chemical Biology · 2018 · 81 citations

Antifungal Agent, Antifungal Agents, Natural Sciences +10

Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors

Natalia Rinis, Jennifer E. Golden, Caleb Marceau et al. · Cell chemical biology · 2018 · 53 citations · Full text

Biochemistry, Natural Sciences, N-glycan Site Occupancy +7

Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications

M.C. Van Zandt, E. Sibley, Erin E. McCann et al. · Bioorganic & Medicinal Chemistry · 2004 · 48 citations

Medicinal Chemistry, Diabetes Management, Aldo-keto Reductase +9