Doug Marcotte

Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases

Kenneth M. Comess, Chaohong Sun, Cele Abad‐Zapatero et al. · ACS Chemical Biology · 2010 · 80 citations

Drug Target, Kinase Inhibitors, Molecular Biology +22

ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis

Bin Ma, Doug Marcotte, Murugan Paramasivam et al. · PLoS ONE · 2016 · 37 citations · Full text

Mitophagy, Apoptosis, Cell Death +16

Structure-based design of low-nanomolar PIM kinase inhibitors

Alexey Ishchenko, Lin Zhang, Jean‐Yves Le Brazidec et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 24 citations · Full text

Engineering, Medicine, Drug Discovery +6

Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor

M.A. Argiriadi, Eric R. Goedken, David Banach et al. · BMC Structural Biology · 2012 · 16 citations · Full text

Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I)

Lin Zhang, Junhua Fan, Jer-Hong Chong et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 10 citations · Full text

Medicinal Chemistry, Potent Multiple-mitotic Kinase, Medicine +11