Jean‐Yves Le Brazidec

Author

Biogen (United States)

Also Known As

Jean-Yves Le Brazidec, Jean‐Yves Le Brazidec

Publications

362

Citations

H-Index

Concepts

All Affiliations

Biogen (United States)Forma Therapeutics (United States)

About

Jean‐Yves Le Brazidec is an author at Biogen (United States) specializing in drug discovery, medicine, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	340
2	Natural Sciences	5	5	289
3	Biochemistry	2	2	198
4	Engineering	1	1	24
5	Biology	1	1	42

Jean‐Yves Le Brazidec

Publications

353

Citations

H-Index

Page 1

	Year	Citations
7‘-Substituted Benzothiazolothio- and Pyridinothiazolothio-Purines as Potent Heat Shock Protein 90 Inhibitors Lin Zhang, Junhua Fan, K. NGUYEN VU, Journal of Medicinal Chemistry Pyridino- ThiazolothiopurinesPharmaceutical ScienceDrug TargetPharmacotherapyChemical Biology	2006	114
Synthesis and Biological Evaluation of a New Class of Geldanamycin Derivatives as Potent Inhibitors of Hsp90 Jean‐Yves Le Brazidec, Adeela Kamal, David J. Busch, Journal of Medicinal Chemistry Pharmaceutical ScienceChemical BiologyPharmaceutical ChemistryDrug ResistanceMedicinal Chemistry	2004	84
Practical entry into the HIJKLM ring segment of ciguatoxin CTX3C Tohru Oishi, Hisatoshi Uehara, Yoko Nagumo, Chemical Communications BiologyHeterocyclicNatural SciencesPractical EntryMolecular Biology	2001	42
Synthesis, SAR and biological evaluation of 1,6-disubstituted-1H-pyrazolo[3,4-d]pyrimidines as dual inhibitors of Aurora kinases and CDK1 Jean‐Yves Le Brazidec, Angela Pasis, Betty Y. Tam, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryDual InhibitorsNatural SciencesMedicineBiological Evaluation	2012	39
Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors Jean‐Yves Le Brazidec, Angela Pasis, Betty Y. Tam, Bioorganic & Medicinal Chemistry Letters Combinatorial ChemistryMedicinal ChemistryMedicineStructure-based DesignPharmacology	2012	27
Structure-based design of low-nanomolar PIM kinase inhibitors Alexey Ishchenko, Lin Zhang, Jean‐Yves Le Brazidec, Bioorganic & Medicinal Chemistry Letters EngineeringMedicineDrug DiscoveryPharmacologyRational Drug Design	2014	24
Stereoselective Synthesis of the C1−C13 Fragment of 2,3-Dihydrodorrigocin A Jean‐Yves Le Brazidec, Charles A. Gilson, Marcus F. Boehm The Journal of Organic Chemistry	2005	13
Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I) Lin Zhang, Junhua Fan, Jer-Hong Chong, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryPotent Multiple-mitotic KinaseMedicineNatural SciencesRational Drug Design	2011	10

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