Chaohong Sun

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Loren Lasko, Clarissa G. Jakob, Rohinton Edalji et al. · Nature · 2017 · 813 citations · Full text

Lineage-specific Tumours, Medicine, Immune Checkpoint Inhibitor +8

Structural Basis for the Inhibition of Caspase-3 by XIAP

Stefan J. Riedl, Martin Renatus, Robert Schwarzenbacher et al. · Cell · 2001 · 784 citations · Full text

Protein Function, Signal Transduction, G Protein-coupled Receptor +7

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

Zhihong Liu, Chaohong Sun, Edward T. Olejniczak et al. · Nature · 2000 · 636 citations

Biochemistry, Natural Sciences, Molecular Biology +4

Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer

Emily J. Faivre, Keith F. McDaniel, Daniel H. Albert et al. · Nature · 2020 · 389 citations

Bd2 Bromodomain, Medicine, Natural Sciences +9

Discovery of Potent Antagonists of the Antiapoptotic Protein XIAP for the Treatment of Cancer

Thorsten Oost, Chaohong Sun, Robert C. Armstrong et al. · Journal of Medicinal Chemistry · 2004 · 363 citations · Full text

Immunology, Cell Death, Antiapoptotic Protein Xiap +18