Clarissa G. Jakob

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Loren Lasko, Clarissa G. Jakob, Rohinton Edalji et al. · Nature · 2017 · 813 citations · Full text

Lineage-specific Tumours, Medicine, Immune Checkpoint Inhibitor +8

The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain

Björn Kauppi, Clarissa G. Jakob, Mathias Färnegårdh et al. · Journal of Biological Chemistry · 2003 · 336 citations · Full text

The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex

Yupeng He, Sujatha Selvaraju, Michael L. Curtin et al. · Nature Chemical Biology · 2017 · 229 citations · Full text

Protein Function, Signal Transduction, Molecular Regulation +7

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

Kenneth D. Bromberg, Taylor R. H. Mitchell, Anup K. Upadhyay et al. · Nature Chemical Biology · 2017 · 127 citations · Full text

Chromatin, Chromatin Remodeling, Epigenetic Change +10

Crystal Structure and Mutagenic Analysis of the Inhibitor-of-Apoptosis Protein Survivin

Steven W. Muchmore, Jun Chen, Clarissa G. Jakob et al. · Molecular Cell · 2000 · 126 citations

Crystal Structure, Biochemistry, Natural Sciences +7