Clarissa G. Jakob

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Loren Lasko, Clarissa G. Jakob, Rohinton Edalji et al. · Nature · 2017 · 858 citations · Full text

Medicine, Cancer Biology, Oncology +8

The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain

Björn Kauppi, Clarissa G. Jakob, Mathias Färnegårdh et al. · Journal of Biological Chemistry · 2003 · 338 citations · Full text

Medicine, Biochemistry, Pharmacology +17

The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex

Yupeng He, Sujatha Selvaraju, Michael L. Curtin et al. · Nature Chemical Biology · 2017 · 233 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +9

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

Kenneth D. Bromberg, Taylor R. H. Mitchell, Anup K. Upadhyay et al. · Nature Chemical Biology · 2017 · 130 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

Crystal Structure and Mutagenic Analysis of the Inhibitor-of-Apoptosis Protein Survivin

Steven W. Muchmore, Jun Chen, Clarissa G. Jakob et al. · Molecular Cell · 2000 · 126 citations

Life Sciences, Cell Biology, Molecular Biology +15