Concepedia

Loren Lasko

LL

Statistics

Publications

15

Citations

2.3K

H-Index

14

Active since

2005

Affiliations

AbbVie (United States)(Current)

Abbott Fund

University of Pennsylvania

Johns Hopkins University

Loren Lasko is an author at AbbVie (United States) specializing in medicine, natural sciences, and drug discovery.

Top concepts

Publications per year

2005–2021

15

Publications

15

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Loren Lasko, Clarissa G. Jakob, Rohinton Edalji et al. · Nature · 2017 · 813 citations · Full text

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ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models

Cherrie K. Donawho, Yan Luo, Yanping Luo et al. · Clinical Cancer Research · 2007 · 762 citations · Full text

ABT-888 Confers Broad <i>In vivo</i> Activity in Combination with Temozolomide in Diverse Tumors

Joann P. Palma, Yichun Wang, Luis E. Rodrı́guez et al. · Clinical Cancer Research · 2009 · 138 citations

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

Kenneth D. Bromberg, Taylor R. H. Mitchell, Anup K. Upadhyay et al. · Nature Chemical Biology · 2017 · 127 citations · Full text

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Acquired Resistance to Combination Treatment with Temozolomide and ABT-888 Is Mediated by Both Base Excision Repair and Homologous Recombination DNA Repair Pathways

Xuesong Liu, Edward K. Han, Mark G. Anderson et al. · Molecular Cancer Research · 2009 · 91 citations

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