Jaclyn L. Henderson

Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases

Debabrata Maiti, Brett P. Fors, Jaclyn L. Henderson et al. · Chemical Science · 2010 · 355 citations

Ligands Brettphos, Palladium-catalyzed Coupling, Most Cases +15

Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7 <i>H</i> -pyrrolo[2,3- <i>d</i> ]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor

Jaclyn L. Henderson, Bethany L. Kormos, Matthew M. Hayward et al. · Journal of Medicinal Chemistry · 2014 · 178 citations · Full text

The Benzyne Aza‐Claisen Reaction

Alastair A. Cant, Guillaume H. V. Bertrand, Jaclyn L. Henderson et al. · Angewandte Chemie International Edition · 2009 · 120 citations

Cross-coupling Reaction, Engineering, Pi Component +10

Biaryl Synthesis via Palladium-Catalyzed Aryne Multicomponent Coupling

Jaclyn L. Henderson, Andrew S. Edwards, Michael F. Greaney · Organic Letters · 2007 · 79 citations

Cross-coupling Reaction, Engineering, Aryl Iodides +9

Efficient Pd-Catalyzed Amination Reactions for Heterocycle Functionalization

Jaclyn L. Henderson, Stephen L. Buchwald · Organic Letters · 2010 · 67 citations

Pd-catalyzed Amination, Cross-coupling Reaction, Structural Types +12