Jaclyn L. Henderson - Concepedia

Author

Jaclyn L. Henderson

Massachusetts Institute of Technology ORCID

Also Known As

Jaclyn Henderson, Jaclyn L. Henderson, Jaclyn L. Henderson

Publications

1.3K

Citations

H-Index

Concepts

All Affiliations

Massachusetts Institute of Technology Pfizer (United States)Biogen (United States)University of Edinburgh

About

Jaclyn L. Henderson is an author at Massachusetts Institute of Technology specializing in chemistry, organic chemistry, and engineering.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Engineering	6	6	738
2	Medicine	5	5	137
3	Biomolecular Engineering	5	5	677
4	Natural Sciences	3	3	394
5	Biochemistry	2	2	375

Jaclyn L. Henderson

Publications

1.1K

Citations

H-Index

Page 1

	Year	Citations
Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases Debabrata Maiti, Brett P. Fors, Jaclyn L. Henderson, Chemical Science Ligands BrettphosPalladium-catalyzed CouplingMost CasesCross-coupling ReactionEngineering	2010	355
Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7 <i>H</i> -pyrrolo[2,3- <i>d</i> ]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor Jaclyn L. Henderson, Bethany L. Kormos, Matthew M. Hayward, Journal of Medicinal Chemistry	2014	178
The Benzyne Aza‐Claisen Reaction Alastair A. Cant, Guillaume H. V. Bertrand, Jaclyn L. Henderson, Angewandte Chemie International Edition Cross-coupling ReactionEngineeringPi ComponentBenzyne Aza‐claisen ReactionOrganic Chemistry	2009	120
Biaryl Synthesis via Palladium-Catalyzed Aryne Multicomponent Coupling Jaclyn L. Henderson, Andrew S. Edwards, Michael F. Greaney Organic Letters Cross-coupling ReactionEngineeringAryl IodidesOrganic ChemistryOrganometallic Catalysis	2007	79
Efficient Pd-Catalyzed Amination Reactions for Heterocycle Functionalization Jaclyn L. Henderson, Stephen L. Buchwald Organic Letters Pd-catalyzed AminationCross-coupling ReactionStructural TypesEngineeringHeterocyclic	2010	67
Palladium-Catalyzed Amination of Unprotected Halo-7-azaindoles Jaclyn L. Henderson, S. McDermott, Stephen L. Buchwald Organic Letters HalogenationAsymmetric CatalysisChemical EngineeringCross-coupling ReactionEngineering	2010	61
Palladium-Catalyzed N-Arylation of 2-Aminothiazoles Meredeth A. McGowan, Jaclyn L. Henderson, Stephen L. Buchwald Organic Letters Broad Substrate ScopeCross-coupling ReactionEngineeringPalladium-catalyzed N-arylationOrganic Chemistry	2012	56
Design and Optimization of Selective Protein Kinase C θ (PKCθ) Inhibitors for the Treatment of Autoimmune Diseases Juan‐Miguel Jimenez, Dean Boyall, Guy Brenchley, Journal of Medicinal Chemistry T-regulatory CellImmunologyImmune RegulationImmunodominanceSelective Pkcθ Inhibitors	2013	46
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo Tamara Halkina, Jaclyn L. Henderson, Edward Yin-Shiang Lin, Journal of Medicinal Chemistry	2021	32
Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffold Paul Galatsis, Jaclyn L. Henderson, Bethany L. Kormos, Bioorganic & Medicinal Chemistry Letters MedicineReceptor Tyrosine KinaseKinase Domain InhibitionMolecular BiologyPharmacology	2014	28

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