Matthew M. Hayward

Delineating the role of cooperativity in the design of potent PROTACs for BTK

Adelajda Zorba, Chuong Nguyen, Yingrong Xu et al. · Proceedings of the National Academy of Sciences · 2018 · 423 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +15

A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors

Bryan Lanning, Landon R. Whitby, Melissa M. Dix et al. · Nature Chemical Biology · 2014 · 363 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +15

Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors

Mark E. Flanagan, J. A. Abramite, Dennis P. Anderson et al. · Journal of Medicinal Chemistry · 2014 · 324 citations

Pharmacy, Chemistry, Medicinal Chemistry +15

Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer

Liron Bar‐Peled, Esther K. Kemper, Radu M. Suciu et al. · Cell · 2017 · 288 citations · Full text

Life Sciences, Molecular Biology, Oncology +12

A proteome-wide atlas of lysine-reactive chemistry

Mikail E. Abbasov, Madeline E. Kavanagh, Taka-Aki Ichu et al. · Nature Chemistry · 2021 · 252 citations · Full text

Life Sciences, Biochemistry, Chemistry +14