Concepedia

Adelajda Zorba

AZ

7

Publications

840

Citations

7

H-Index

2003

Active since

Affiliations

Brandeis University(Current)

Howard Hughes Medical Institute

Adelajda Zorba is an author at Brandeis University specializing in systems biology, signal transduction, and drug discovery.

Top concepts

MedicineCell BiologyDrug DiscoverySystems BiologyMolecular BiologySignal TransductionChemistryCell SignalingNatural SciencesMolecular Docking

Publications per year

2003–2019

7

Publications

7

Delineating the role of cooperativity in the design of potent PROTACs for BTK

Adelajda Zorba, Chuong Nguyen, Yingrong Xu et al. · Proceedings of the National Academy of Sciences · 2018 · 409 citations · Full text

Engineering, Molecular Biology, Organic Chemistry +18

Using ancient protein kinases to unravel a modern cancer drug’s mechanism

Christopher Wilson, Roman V. Agafonov, Marc Hoemberger et al. · Science · 2015 · 171 citations · Full text

Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2

Adelajda Zorba, Vanessa Buosi, S. Kutter et al. · eLife · 2014 · 129 citations · Full text

Allosteric modulation of a human protein kinase with monobodies

Adelajda Zorba, Vy Nguyen, Akiko Koide et al. · Proceedings of the National Academy of Sciences · 2019 · 51 citations · Full text

Drug Target, Atp Binding Site, Strong Kinase Inhibitors +17

Dynamics of human protein kinase Aurora A linked to drug selectivity

Warintra Pitsawong, Vanessa Buosi, Renee Otten et al. · eLife · 2018 · 47 citations · Full text

Drug Selectivity, Drug Target, Kinase Inhibitors +16

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