Chuong Nguyen

Delineating the role of cooperativity in the design of potent PROTACs for BTK

Adelajda Zorba, Chuong Nguyen, Yingrong Xu et al. · Proceedings of the National Academy of Sciences · 2018 · 409 citations · Full text

Engineering, Molecular Biology, Organic Chemistry +18

Systems-wide Proteomic Analysis in Mammalian Cells Reveals Conserved, Functional Protein Turnover

Sidney Cambridge, Florian Gnad, Chuong Nguyen et al. · Journal of Proteome Research · 2011 · 284 citations

Protein Turnover, Genetics, Proteasome +22

PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor

Hua Xu, Michael I. Jesson, Uthpala Seneviratne et al. · ACS Chemical Biology · 2019 · 152 citations

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

Ryan M. Esquejo, Christopher T. Salatto, Jake Delmore et al. · EBioMedicine · 2018 · 146 citations · Full text

Phosphoproteomic evaluation of pharmacological inhibition of leucine‐<scp>rich</scp> repeat kinase 2 reveals significant off‐target effects of <scp>LRRK</scp>‐2‐<scp>IN</scp>‐1

Gregory C. Luerman, Chuong Nguyen, Harry Samaroo et al. · Journal of Neurochemistry · 2013 · 65 citations · Full text

Mitophagy, Lrrk2 Kinase Inhibition, Molecular Biology +18