Concepedia

Hua Xu

HX

Statistics

Publications

8

Citations

502

H-Index

8

Active since

2013

Affiliations

Pfizer (United States)(Current)

Institute of Biophysics

Foton Motors (China)

Institute of Molecular Biology and Biophysics

Hua Xu is an author at Pfizer (United States) specializing in drug discovery, molecular probe development, and ligand binding.

Publications per year

2013–2019

8

Publications

8

Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes

Erik C. Hett, Hua Xu, Kieran F. Geoghegan et al. · ACS Chemical Biology · 2015 · 192 citations

Pharmacy, Chemical Biology, Molecular Biology +16

PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor

Hua Xu, Michael I. Jesson, Uthpala Seneviratne et al. · ACS Chemical Biology · 2019 · 161 citations

Life Sciences, Medicinal Chemistry, Pharmacology +15

Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

Shenping Liu, Leslie Dakin, Xing Li et al. · Scientific Reports · 2016 · 62 citations · Full text

Pharmacy, Immunology, Medicinal Chemistry +17

Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells

Hua Xu, Ariamala Gopalsamy, Erik C. Hett et al. · Organic & Biomolecular Chemistry · 2016 · 25 citations

Life Sciences, Biochemistry, Molecular Biology +17

Kinetic Characterization of Hydrolysis of Nitrocefin, Cefoxitin, and Meropenem by β-Lactamase from<i>Mycobacterium tuberculosis</i>

Carmen Chow, Hua Xu, John S. Blanchard · Biochemistry · 2013 · 23 citations

Life Sciences, Biochemistry, Microbiology +17

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