Concepedia

Hua Xu

HX

8

Publications

488

Citations

8

H-Index

2013

Active since

Affiliations

Pfizer (United States)(Current)

Institute of Biophysics

Foton Motors (China)

Institute of Molecular Biology and Biophysics

Hua Xu is an author at Pfizer (United States) specializing in drug discovery, medicine, and natural sciences.

Top concepts

MedicineBiochemistryPharmacologyDrug DiscoveryNatural SciencesChemistryBiometricsBiophysicsBioanalysisEngineering

Publications per year

2013–2019

8

Publications

8

Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes

Erik C. Hett, Hua Xu, Kieran F. Geoghegan et al. · ACS Chemical Biology · 2015 · 191 citations

Molecular Pharmacology, Drug Target, Biochemistry +15

PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor

Hua Xu, Michael I. Jesson, Uthpala Seneviratne et al. · ACS Chemical Biology · 2019 · 152 citations

Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

Shenping Liu, Leslie Dakin, Xing Li et al. · Scientific Reports · 2016 · 60 citations · Full text

Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells

Hua Xu, Ariamala Gopalsamy, Erik C. Hett et al. · Organic & Biomolecular Chemistry · 2016 · 24 citations

Drug Target, Bioanalysis, Enzyme Affinity +18

Kinetic Characterization of Hydrolysis of Nitrocefin, Cefoxitin, and Meropenem by β-Lactamase from<i>Mycobacterium tuberculosis</i>

Carmen Chow, Hua Xu, John S. Blanchard · Biochemistry · 2013 · 22 citations · Full text

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