Melissa M. Dix

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

Xiaoyu Zhang, Vincent M. Crowley, Thomas Wucherpfennig et al. · Nature Chemical Biology · 2019 · 461 citations

Protein Degradation, Protein Function, Molecular Biology +1

Global Mapping of the Topography and Magnitude of Proteolytic Events in Apoptosis

Melissa M. Dix, Gabriel M. Simon, Benjamin F. Cravatt · Cell · 2008 · 364 citations · Full text

Signal Transduction, Proteolytic Events, Cell Division +11

A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors

Bryan Lanning, Landon R. Whitby, Melissa M. Dix et al. · Nature Chemical Biology · 2014 · 356 citations · Full text

Molecular Docking, Drug Target, Biochemistry +10

An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells

Ekaterina V. Vinogradova, Xiaoyu Zhang, David Remillard et al. · Cell · 2020 · 352 citations · Full text

Electrophile-cysteine Interactions, Signal Transduction, Biochemistry +10

Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer

Liron Bar‐Peled, Esther K. Kemper, Radu M. Suciu et al. · Cell · 2017 · 283 citations · Full text

Medicine, Natural Sciences, Proteomics +8