Vincent M. Crowley

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

Xiaoyu Zhang, Vincent M. Crowley, Thomas Wucherpfennig et al. · Nature Chemical Biology · 2019 · 461 citations

Protein Degradation, Protein Function, Molecular Biology +1

An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells

Ekaterina V. Vinogradova, Xiaoyu Zhang, David Remillard et al. · Cell · 2020 · 352 citations · Full text

Electrophile-cysteine Interactions, Signal Transduction, Biochemistry +10

A proteome-wide atlas of lysine-reactive chemistry

Mikail E. Abbasov, Madeline E. Kavanagh, Taka-Aki Ichu et al. · Nature Chemistry · 2021 · 237 citations · Full text

Protein Chemistry, Proteomic Technology, Biochemistry +3

DCAF11 Supports Targeted Protein Degradation by Electrophilic Proteolysis-Targeting Chimeras

Xiaoyu Zhang, Lena Luukkonen, Christie L. Eissler et al. · Journal of the American Chemical Society · 2021 · 183 citations · Full text

Proteomic Technology, Androgen Receptor, Protein Function +14

Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold

Vincent M. Crowley, Anuj Khandelwal, Sanket J. Mishra et al. · Journal of Medicinal Chemistry · 2016 · 65 citations · Full text