Bethany L. Kormos

Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

Antonia F. Stepan, Chakrapani Subramanyam, Ivan Efremov et al. · Journal of Medicinal Chemistry · 2012 · 412 citations · Full text

Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7 <i>H</i> -pyrrolo[2,3- <i>d</i> ]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor

Jaclyn L. Henderson, Bethany L. Kormos, Matthew M. Hayward et al. · Journal of Medicinal Chemistry · 2014 · 178 citations · Full text

Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs

John D. McCorvy, Kyle V. Butler, Brendan Kelly et al. · Nature Chemical Biology · 2017 · 175 citations · Full text

Medicine, Rational Drug Design, Pharmacology +3

Do Collective Atomic Fluctuations Account for Cooperative Effects? Molecular Dynamics Studies of the U1A−RNA Complex

Bethany L. Kormos, Anne M. Baranger, David L. Beveridge · Journal of the American Chemical Society · 2006 · 55 citations · Full text

Dopamine D3 receptor antagonist reveals a cryptic pocket in aminergic GPCRs

Noelia Ferruz, Stefan Doerr, Michelle Vanase‐Frawley et al. · Scientific Reports · 2018 · 53 citations · Full text