Kyle V. Butler - Concepedia

Author

Kyle V. Butler

Also Known As

Butler, Kyle V., Frye, Stephen V., K. Butler, Kyle Butler, Kyle V Butler, Kyle V. Butler, Kyle Vincent Butler, Kyle V. Butler

Publications

2.4K

Citations

H-Index

Concepts

All Affiliations

Icahn School of Medicine at Mount Sinai Structural Genomics Consortium University of North Carolina at Chapel Hill University of Toronto University of Illinois Chicago

About

Kyle V. Butler is an author at Icahn School of Medicine at Mount Sinai specializing in medicine, natural sciences, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	1.7K
2	Natural Sciences	8	8	1.4K
3	Biochemistry	7	7	1.3K
4	Biomolecular Engineering	2	2	302
5	Cell Biology	2	2	184

Kyle V. Butler

Publications

2.2K

Citations

H-Index

Page 1

	Year	Citations
Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A Kyle V. Butler, Jay H. Kalin, Camille Brochier, Journal of the American Chemical Society PharmacotherapyChemical BiologyPharmaceutical ChemistryMedicinal ChemistryRational Design	2010	755
A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases Mohammad S. Eram, Yudao Shen, Magdalena M. Szewczyk, ACS Chemical Biology Drug TargetEpigenetic ChangeMolecular BiologyType Iii PrmtsChemical Biology	2015	280
Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3 <sup>+</sup> T-Regulatory Cells Edwin F. de Zoeten, Liqing Wang, Kyle V. Butler, Molecular and Cellular Biology	2011	250
Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs John D. McCorvy, Kyle V. Butler, Brendan Kelly, Nature Chemical Biology MedicineRational Drug DesignPharmacologyMolecular ModelingStructure-inspired Design	2017	175
Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8 Anqi Ma, Wenyu Yu, Fengling Li, Journal of Medicinal Chemistry Histone ModificationsDrug TargetEpigenetic ChangeMolecular BiologyChemical Biology	2014	108
Second-Generation Histone Deacetylase 6 Inhibitors Enhance the Immunosuppressive Effects of Foxp3+ T-Regulatory Cells Jay H. Kalin, Kyle V. Butler, Tatiana Akimova, Journal of Medicinal Chemistry Fold SelectivityT-regulatory CellImmunologyImmune RegulationRegulatory T Cells	2011	102
Novel Inhibitors of Human Histone Deacetylase (HDAC) Identified by QSAR Modeling of Known Inhibitors, Virtual Screening, and Experimental Validation Xiang S. Wang, Xi‐Ping Huang, Bryan L. Roth, Journal of Chemical Information and Modeling	2009	100
Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery Anna M. Chiarella, Kyle V. Butler, Berkley E. Gryder, Nature Biotechnology Dose-dependent ActivationChromatinOff-target EffectChromatin RemodelingNatural Sciences	2019	82
Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists Xin Chen, John D. McCorvy, Matthew G. Fischer, Journal of Medicinal Chemistry Drug TargetPharmacotherapyPre-clinical PharmacologySystems PharmacologyMolecular Pharmacology	2016	52
Nitroimidazole Derivatives. Relationship between Structure and Antitrichomonal Activity Kyle V. Butler, Harold L. Howes, Joseph E. Lynch, Journal of Medicinal Chemistry Pharmaceutical ScienceAltmetric Attention ScorePharmacotherapyChemical BiologyPharmaceutical Chemistry	1967	49

Page 1