Jay H. Kalin

Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A

Kyle V. Butler, Jay H. Kalin, Camille Brochier et al. · Journal of the American Chemical Society · 2010 · 772 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

Jay H. Kalin, Muzhou Wu, Andrea V. Gómez et al. · Nature Communications · 2018 · 233 citations · Full text

Medicine, Oncology, Pharmacology +16

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

Jamie N. Anastas, Barry M. Zee, Jay H. Kalin et al. · Cancer Cell · 2019 · 191 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells

Brian Budke, Hillary L. Logan, Jay H. Kalin et al. · Nucleic Acids Research · 2012 · 179 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition

Maj-Linda B. Selenica, Leif Benner, Steven B. Housley et al. · Alzheimer s Research & Therapy · 2014 · 135 citations · Full text

Life Sciences, Neurology, Neuroscience +17