Mohammad S. Eram

A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases

Mohammad S. Eram, Yudao Shen, Magdalena M. Szewczyk et al. · ACS Chemical Biology · 2015 · 292 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +5

LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity

Zahid Bonday, Guillermo S. Cortez, Michael J. Grogan et al. · ACS Medicinal Chemistry Letters · 2018 · 181 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma

Kazuhide Nakayama, Magdalena M. Szewczyk, Carlo dela Seña et al. · Oncotarget · 2018 · 144 citations · Full text

Medicine, Oncology, Pharmacology +10

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

Kenneth D. Bromberg, Taylor R. H. Mitchell, Anup K. Upadhyay et al. · Nature Chemical Biology · 2017 · 130 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

A Potent, Selective and Cell‐Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)

H. Ümit Kanıskan, Magdalena M. Szewczyk, Zhengtian Yu et al. · Angewandte Chemie International Edition · 2015 · 127 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17