Paul Faulder

Small Molecule Binding Sites on the Ras:SOS Complex Can Be Exploited for Inhibition of Ras Activation

Jon Winter, Malcolm Anderson, Kevin Blades et al. · Journal of Medicinal Chemistry · 2015 · 120 citations

Life Sciences, Biochemistry, Molecular Biology +17

Coumarin-Based Inhibitors of Human NAD(P)H:Quinone Oxidoreductase-1. Identification, Structure–Activity, Off-Target Effects and In Vitro Human Pancreatic Cancer Toxicity

Karen A. Nolan, He Zhao, Paul Faulder et al. · Journal of Medicinal Chemistry · 2007 · 73 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Inhibiting NF-κB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure–activity relationship, and co-crystal structures

Kexue Li, Lawrence R. McGee, Ben Fisher et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +17

QM/MM Studies Show Substantial Tunneling for the Hydrogen-Transfer Reaction in Methylamine Dehydrogenase

Paul Faulder, Gary Tresadern, Kamaldeep K. Chohan et al. · Journal of the American Chemical Society · 2001 · 64 citations

Natural Sciences, Biochemistry, Chemistry +15

Diverse Heterocyclic Scaffolds as Allosteric Inhibitors of AKT

Jason G. Kettle, S Brown, Claire Crafter et al. · Journal of Medicinal Chemistry · 2012 · 51 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17