Claire Crafter

Preclinical Pharmacology of AZD5363, an Inhibitor of AKT: Pharmacodynamics, Antitumor Activity, and Correlation of Monotherapy Activity with Genetic Background

Barry R. Davies, Hannah E. Greenwood, Phillippa Dudley et al. · Molecular Cancer Therapeutics · 2012 · 453 citations

Pharmacotherapy, Cancer Biology, Tumor Biology +18

AZD1152, a Selective Inhibitor of Aurora B Kinase, Inhibits Human Tumor Xenograft Growth by Inducing Apoptosis

Robert W. Wilkinson, Rajesh Odedra, Simon P. Heaton et al. · Clinical Cancer Research · 2007 · 355 citations · Full text

Validating Aurora B as an anti-cancer drug target

Fiona Girdler, Karen E. Gascoigne, Patrick A. Eyers et al. · Journal of Cell Science · 2006 · 283 citations · Full text

Aurora B, Cell Cycle, Cancer Biology +18

Discovery, Synthesis, and <i>in Vivo</i> Activity of a New Class of Pyrazoloquinazolines as Selective Inhibitors of Aurora B Kinase

Andrew Mortlock, Kevin M. Foote, Nicola M. Heron et al. · Journal of Medicinal Chemistry · 2007 · 270 citations · Full text

Pharmaceutical Science, Selective Inhibitors, Pharmacotherapy +17

Combined Inhibition of mTOR and CDK4/6 Is Required for Optimal Blockade of E2F Function and Long-term Growth Inhibition in Estrogen Receptor–positive Breast Cancer

Chrysiis Michaloglou, Claire Crafter, Oona Delpuech et al. · Molecular Cancer Therapeutics · 2018 · 188 citations · Full text