Karen E. Gascoigne - Concepedia

Author

Karen E. Gascoigne

Whitehead Institute for Biomedical Research ORCID

Also Known As

Gascoigne, Karen, Gascoigne, Karen E., K.E. Gascoigne, Karen E Gascoigne, Karen E. Gascoigne, Karen Gascoigne, Karen E. Gascoigne

Publications

Citations

H-Index

Concepts

All Affiliations

Whitehead Institute for Biomedical Research WuXi AppTec (China)Massachusetts Institute of Technology University of Manchester Constellation Pharmaceuticals (United States)

About

Karen E. Gascoigne is an author at Whitehead Institute for Biomedical Research specializing in medicine, cell biology, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	2.2K
2	Cell Biology	10	10	1.9K
3	Natural Sciences	4	4	672
4	Immunology	2	2	189
5	Engineering	1	1	31

Karen E. Gascoigne

Publications

3.5K

Citations

H-Index

Page 1

	Year	Citations
Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs Karen E. Gascoigne, Stephen S. Taylor Cancer Cell Antimitotic DrugsOncologyMedicinePharmacologyProlonged Exposure	2008	820
Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation Ryan Raisner, Samir Kharbanda, Lingyan Jin, Cell Reports	2018	398
Induced Ectopic Kinetochore Assembly Bypasses the Requirement for CENP-A Nucleosomes Karen E. Gascoigne, K. Takeuchi, Aussie Suzuki, Cell ChromatinChromatin StructureCell DivisionChromatin RemodelingNatural Sciences	2011	345
Validating Aurora B as an anti-cancer drug target Fiona Girdler, Karen E. Gascoigne, Patrick A. Eyers, Journal of Cell Science Aurora BCell CycleCancer BiologySpindle Checkpoint FunctionTumor Biology	2006	283
CENP-T-W-S-X Forms a Unique Centromeric Chromatin Structure with a Histone-like Fold Tatsuya Nishino, K. Takeuchi, Karen E. Gascoigne, Cell ChromatinChromatin StructureChromatin RemodelingCenp-t-w-s-x FormsNatural Sciences	2012	261
Antibody Conjugation of a Chimeric BET Degrader Enables <i>in vivo</i> Activity Thomas H. Pillow, Pragya Adhikari, Robert A. Blake, ChemMedChem	2019	178
Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer Lingyan Jin, Jesse Garcia, Emily Chan, Cancer Research	2017	149
Distinct Organization and Regulation of the Outer Kinetochore KMN Network Downstream of CENP-C and CENP-T Florencia Rago, Karen E. Gascoigne, Iain M. Cheeseman Current Biology Signal TransductionCell DivisionDistinct OrganizationMolecular BiologyCytoskeleton	2015	143
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake, Journal of Medicinal Chemistry	2021	140
GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) F. Anthony Romero, Jeremy Murray, Kwong Wah Lai, Journal of Medicinal Chemistry	2017	125

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