Oona Delpuech

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP

Thomas Porstmann, B Griffiths, Yuen‐Li Chung et al. · Oncogene · 2005 · 448 citations

Life Sciences, Biochemistry, Molecular Biology +12

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

Emma C. Ferber, Barrie Peck, Oona Delpuech et al. · Cell Death and Differentiation · 2011 · 314 citations

Life Sciences, Genetics, Molecular Biology +14

Combined Inhibition of mTOR and CDK4/6 Is Required for Optimal Blockade of E2F Function and Long-term Growth Inhibition in Estrogen Receptor–positive Breast Cancer

Chrysiis Michaloglou, Claire Crafter, Oona Delpuech et al. · Molecular Cancer Therapeutics · 2018 · 190 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Induction of Mxi1-SR<i>α</i> by FOXO3a Contributes to Repression of Myc-Dependent Gene Expression

Oona Delpuech, B Griffiths, Philip East et al. · Molecular and Cellular Biology · 2007 · 162 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

AZD2014, an Inhibitor of mTORC1 and mTORC2, Is Highly Effective in ER+ Breast Cancer When Administered Using Intermittent or Continuous Schedules

Sylvie M. Guichard, Jon Curwen, Teeru Bihani et al. · Molecular Cancer Therapeutics · 2015 · 125 citations · Full text

Medicine, Oncology, Pharmacology +17