Oona Delpuech

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP

Thomas Porstmann, B Griffiths, Yuen‐Li Chung et al. · Oncogene · 2005 · 442 citations

Systems Biology, Signal Transduction, Molecular Physiology +12

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

Emma C. Ferber, Barrie Peck, Oona Delpuech et al. · Cell Death and Differentiation · 2011 · 302 citations · Full text

Mitochondrial Function, Physiology, Gene Expression +8

Combined Inhibition of mTOR and CDK4/6 Is Required for Optimal Blockade of E2F Function and Long-term Growth Inhibition in Estrogen Receptor–positive Breast Cancer

Chrysiis Michaloglou, Claire Crafter, Oona Delpuech et al. · Molecular Cancer Therapeutics · 2018 · 188 citations · Full text

Induction of Mxi1-SR<i>α</i> by FOXO3a Contributes to Repression of Myc-Dependent Gene Expression

Oona Delpuech, B Griffiths, Philip East et al. · Molecular and Cellular Biology · 2007 · 160 citations · Full text

Forkhead Transcription Factors, Molecular Regulation, Genetics +18

AZD2014, an Inhibitor of mTORC1 and mTORC2, Is Highly Effective in ER+ Breast Cancer When Administered Using Intermittent or Continuous Schedules

Sylvie M. Guichard, Jon Curwen, Teeru Bihani et al. · Molecular Cancer Therapeutics · 2015 · 125 citations · Full text

Breast Oncology, Chemoprevention Strategy, Pharmacotherapy +18