Sylvie M. Guichard

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, Fábio Camargo Abdalla, Hagai Abeliovich et al. · Autophagy · 2012 · 4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with <i>In vitro</i> and <i>In vivo</i> Antitumor Activity

Christine M. Chresta, Barry R. Davies, Ian Hickson et al. · Cancer Research · 2009 · 795 citations · Full text

Medicine, Oncology, Pharmacology +13

Kinase-Substrate Enrichment Analysis Provides Insights into the Heterogeneity of Signaling Pathway Activation in Leukemia Cells

Pedro Casado, Juan‐Carlos Rodríguez‐Prados, Sabina Cosulich et al. · Science Signaling · 2013 · 470 citations

Life Sciences, Cell Biology, Oncology +11

mTOR Kinase Inhibition Causes Feedback-Dependent Biphasic Regulation of AKT Signaling

Vanessa Rodrik-Outmezguine, Sarat Chandarlapaty, Nen C. Pagano et al. · Cancer Discovery · 2011 · 433 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent

Kevin M. Foote, J. Willem M. Nissink, Thomas M. McGuire et al. · Journal of Medicinal Chemistry · 2018 · 331 citations · Full text

Medicine, Oncology, Pharmacology +16