Nen C. Pagano

Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

Miki Hayano, Wushuang Yang, C K Corn et al. · Cell Death and Differentiation · 2015 · 445 citations · Full text

Biosynthesis, Cellular Enzymology, Biochemistry +10

mTOR Kinase Inhibition Causes Feedback-Dependent Biphasic Regulation of AKT Signaling

Vanessa Rodrik-Outmezguine, Sarat Chandarlapaty, Nen C. Pagano et al. · Cancer Discovery · 2011 · 428 citations · Full text

Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity

Miki Hayano, Nen C. Pagano, Brent R. Stockwell · Cell chemical biology · 2016 · 292 citations · Full text

Reductive Stress, Biochemistry, Helps Identify Nadph +13

Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma

Jonathan H. Schatz, Elisa Oricchio, Andrew L. Wolfe et al. · The Journal of Experimental Medicine · 2011 · 114 citations · Full text

Pim Kinases, Kinase Inhibitors, Pim-mediated Resistance +17

Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells

Eduard Reznik, Michael E. Stokes, Lakshmi Krishnamoorthy et al. · Cell chemical biology · 2018 · 107 citations · Full text

Neuro-oncology, Medicine, Bioactive Metal +10