Thomas M. McGuire - Concepedia

Author

Thomas M. McGuire

Also Known As

McGuire, T.M., McGuire, Thomas, McGuire, Thomas M., T. M. MCGUIRE, T. M. McGuire, T. M. Mcguire, T.M. McGuire, Thomas M. McGuire, Thomas McGuire

106

Publications

2.9K

Citations

H-Index

Concepts

All Affiliations

AstraZeneca (United Kingdom)University of Bath University of Oxford AstraZeneca (United States)Oxford Research Group

About

Thomas M. McGuire is an author at AstraZeneca (United Kingdom) specializing in chemistry, organic chemistry, and engineering.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Engineering	12	13	852
2	Biomolecular Engineering	11	11	561
3	Natural Sciences	10	10	969
4	Medicine	8	8	782
5	Biochemistry	7	7	319

Thomas M. McGuire

Publications

2.8K

Citations

H-Index

Page 1

	Year	Citations
KO<i>t</i>Bu: A Privileged Reagent for Electron Transfer Reactions? Joshua P. Barham, Graeme Coulthard, Katie J. Emery, Journal of the American Chemical Society EngineeringSingle Electron TransferProton-coupled Electron TransferOrganic ChemistryChemistry	2016	313
Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent Kevin M. Foote, J. Willem M. Nissink, Thomas M. McGuire, Journal of Medicinal Chemistry Kinase Ataxia TelangiectasiaCell DeathMolecular BiologyPharmacotherapyCompound 2	2018	313
Discovery of 4-{4-[(3<i>R</i>)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1<i>H</i>-indole (AZ20): A Potent and Selective Inhibitor of ATR Protein Kinase with Monotherapy in Vivo Antitumor Activity Kevin M. Foote, Kevin Blades, Anna Cronin, Journal of Medicinal Chemistry Compound 6PharmacotherapyPharmaceutical ChemistryTumor BiologyMedicinal Chemistry	2013	213
The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2<i>H</i>-pyran-4-yl)-1,3-dihydro-2<i>H</i>-imidazo[4,5-<i>c</i>]quinolin-2-one) Kurt G. Pike, Bernard Barlaam, Elaine Cadogan, Journal of Medicinal Chemistry	2018	111
Synthesis of 5- to 8-membered cyclic carbonates from diols and CO2: A one-step, atmospheric pressure and ambient temperature procedure Thomas M. McGuire, Eva M. López‐Vidal, Georgina L. Gregory, Journal of CO2 Utilization Chemical EngineeringCarbonizationEngineering8-Membered Cyclic CarbonatesAtmospheric Pressure	2018	104
Chemical Recycling of Commercial Poly(<scp>l</scp>-lactic acid) to <scp>l</scp>-Lactide Using a High-Performance Sn(II)/Alcohol Catalyst System Thomas M. McGuire, Antoine Buchard, Charlotte K. Williams Journal of the American Chemical Society	2023	100
Electron Transfer Reactions: KO<i>t</i>Bu (but not NaO<i>t</i>Bu) Photoreduces Benzophenone under Activation by Visible Light Giuseppe Nocera, Allan Young, F. Palumbo, Journal of the American Chemical Society	2018	98
Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies Bernard Barlaam, Robert Casella, Justin Cidado, Journal of Medicinal Chemistry	2020	98
Solid-State Chemical Recycling of Polycarbonates to Epoxides and Carbon Dioxide Using a Heterodinuclear Mg(II)Co(II) Catalyst Thomas M. McGuire, Arron C. Deacy, Antoine Buchard, Journal of the American Chemical Society	2022	86
Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC) Richard A. Ward, Mark J. Anderton, Paul A. Bethel, Journal of Medicinal Chemistry	2019	75

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