Thomas M. McGuire

KO<i>t</i>Bu: A Privileged Reagent for Electron Transfer Reactions?

Joshua P. Barham, Graeme Coulthard, Katie J. Emery et al. · Journal of the American Chemical Society · 2016 · 313 citations · Full text

Engineering, Single Electron Transfer, Proton-coupled Electron Transfer +16

Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent

Kevin M. Foote, J. Willem M. Nissink, Thomas M. McGuire et al. · Journal of Medicinal Chemistry · 2018 · 313 citations · Full text

Kinase Ataxia Telangiectasia, Cell Death, Molecular Biology +19

Discovery of 4-{4-[(3<i>R</i>)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1<i>H</i>-indole (AZ20): A Potent and Selective Inhibitor of ATR Protein Kinase with Monotherapy in Vivo Antitumor Activity

Kevin M. Foote, Kevin Blades, Anna Cronin et al. · Journal of Medicinal Chemistry · 2013 · 213 citations · Full text

Compound 6, Pharmacotherapy, Pharmaceutical Chemistry +17

The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2<i>H</i>-pyran-4-yl)-1,3-dihydro-2<i>H</i>-imidazo[4,5-<i>c</i>]quinolin-2-one)

Kurt G. Pike, Bernard Barlaam, Elaine Cadogan et al. · Journal of Medicinal Chemistry · 2018 · 111 citations · Full text

Synthesis of 5- to 8-membered cyclic carbonates from diols and CO2: A one-step, atmospheric pressure and ambient temperature procedure

Thomas M. McGuire, Eva M. López‐Vidal, Georgina L. Gregory et al. · Journal of CO2 Utilization · 2018 · 104 citations

Chemical Engineering, Carbonization, Engineering +8