Thomas M. McGuire

Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent

Kevin M. Foote, J. Willem M. Nissink, Thomas M. McGuire et al. · Journal of Medicinal Chemistry · 2018 · 331 citations · Full text

Medicine, Oncology, Pharmacology +16

KO<i>t</i>Bu: A Privileged Reagent for Electron Transfer Reactions?

Joshua P. Barham, Graeme Coulthard, Katie J. Emery et al. · Journal of the American Chemical Society · 2016 · 326 citations · Full text

Natural Sciences, Chemistry, Computational Chemistry +16

Discovery of 4-{4-[(3<i>R</i>)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1<i>H</i>-indole (AZ20): A Potent and Selective Inhibitor of ATR Protein Kinase with Monotherapy in Vivo Antitumor Activity

Kevin M. Foote, Kevin Blades, Anna Cronin et al. · Journal of Medicinal Chemistry · 2013 · 215 citations · Full text

Medicine, Oncology, Pharmacology +13

The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2<i>H</i>-pyran-4-yl)-1,3-dihydro-2<i>H</i>-imidazo[4,5-<i>c</i>]quinolin-2-one)

Kurt G. Pike, Bernard Barlaam, Elaine Cadogan et al. · Journal of Medicinal Chemistry · 2018 · 116 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Chemical Recycling of Commercial Poly(<scp>l</scp>-lactic acid) to <scp>l</scp>-Lactide Using a High-Performance Sn(II)/Alcohol Catalyst System

Thomas M. McGuire, Antoine Buchard, Charlotte K. Williams · Journal of the American Chemical Society · 2023 · 114 citations · Full text

Engineering, Chemical Engineering, Chemistry +17