S Brown

Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor

M. Raymond V. Finlay, Mark J. Anderton, Susan Ashton et al. · Journal of Medicinal Chemistry · 2014 · 590 citations · Full text

Genetics, Pathology, Clinical Candidate +18

Diverse Heterocyclic Scaffolds as Allosteric Inhibitors of AKT

Jason G. Kettle, S Brown, Claire Crafter et al. · Journal of Medicinal Chemistry · 2012 · 51 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Downstream Biomarkers +12

Current Treatment and Outcomes Benchmark for Locally Advanced or Metastatic Urothelial Cancer From a Large UK-Based Single Centre

Sue Cheeseman, Matthew D. Thompson, Will Sopwith et al. · Frontiers in Oncology · 2020 · 29 citations · Full text

Modulators of the human CCR5 receptor. Part 3: SAR of substituted 1-[3-(4-methanesulfonylphenyl)-3-phenylpropyl]-piperidinyl phenylacetamides

John G. Cumming, S Brown, Anne Cooper et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 19 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Functional Selectivity +12