Gary Tresadern - Concepedia

Author

Gary Tresadern

Also Known As

G Tresadern, G. Tresadern, GARY TRESADERN, Gary J. Tresadern, Gary John Tresadern, Gary Tresadern, Schindler, Christina E. M., Tresadern, Gary, Tresadern, Gary J.

164

Publications

4.5K

Citations

H-Index

Concepts

All Affiliations

Janssen (Belgium)Universitat Autònoma de Barcelona University of California, Irvine Janssen (United States)Leiden University

About

Gary Tresadern is an author at Janssen (Belgium) specializing in medicine, drug discovery, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	21	29	1.3K
2	Natural Sciences	20	22	1.2K
3	Biochemistry	20	24	1.2K
4	Engineering	15	18	701
5	Social Sciences	2	2	73

Gary Tresadern

Publications

3.6K

Citations

H-Index

Page 1

	Year	Citations
Large scale relative protein ligand binding affinities using non-equilibrium alchemy Vytautas Gapsys, Laura Pérez‐Benito, Matteo Aldeghi, Chemical Science	2019	285
Development and Benchmarking of Open Force Field v1.0.0—the Parsley Small-Molecule Force Field Yudong Qiu, Daniel G. A. Smith, Simon Boothroyd, Journal of Chemical Theory and Computation EngineeringComputational ChemistryChemistryMolecular DesignSingle Molecule Biophysics	2021	163
Application of Free Energy Perturbation for the Design of BACE1 Inhibitors Myriam Ciordia, Laura Pérez‐Benito, Francisca Delgado, Journal of Chemical Information and Modeling Chemical BiologyPharmaceutical ChemistryFep CalculationsMolecular PharmacologyMedicinal Chemistry	2016	118
Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor Radovan Spurný, Sarah Debaveye, Ana Farinha, Proceedings of the National Academy of Sciences	2015	115
Acylguanidine Beta Secretase 1 Inhibitors: A Combined Experimental and Free Energy Perturbation Study Henrik Keränen, Laura Pérez‐Benito, Myriam Ciordia, Journal of Chemical Theory and Computation Core Hopping Fep+Peptide SciencePharmacotherapyChemical BiologyFep Calculations	2017	92
Alchemical absolute protein–ligand binding free energies for drug design Yuriy Khalak, Gary Tresadern, Matteo Aldeghi, Chemical Science	2021	87
Benzazaborinines as Novel Bioisosteric Replacements of Naphthalene: Propranolol as an Example Frederik Rombouts, Fulgencio Tovar, Nigel Austin, Journal of Medicinal Chemistry	2015	86
Chemical Space Exploration with Active Learning and Alchemical Free Energies Yuriy Khalak, Gary Tresadern, David F. Hahn, Journal of Chemical Theory and Computation Drug TargetEngineeringMachine LearningChemical AnalysisHit Identification	2022	86
Discovery of 3-Cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl[1,2,4]triazolo[4,3-<i>a</i>]pyridine (JNJ-42153605): A Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor José M. Cid, Gary Tresadern, Juan A. Vega, Journal of Medicinal Chemistry Rem Sleep StatePharmacotherapyMglu2 Receptor PamsExperimental PharmacologyPre-clinical Pharmacology	2012	84
Accurate Prediction of GPCR Ligand Binding Affinity with Free Energy Perturbation Francesca Deflorian, Laura Pérez‐Benito, Eelke B. Lenselink, Journal of Chemical Information and Modeling	2020	82

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