Concepedia

Toshihiro Imaeda

TI

Statistics

Publications

22

Citations

1.3K

H-Index

16

Active since

1989

Affiliations

Takeda (Japan)(Current)

Tri-Institutional Therapeutics Discovery Institute

Cornell University

Weill Cornell Medicine

Schrodinger (United States)

Toshihiro Imaeda is an author at Takeda (Japan) specializing in drug discovery, medicinal chemistry, and pharmacology.

Publications per year

1989–2023

22

Publications

22

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

Jessica Vincent, Carolina Adura, Pu Gao et al. · Nature Communications · 2017 · 372 citations · Full text

, , +17

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

Lodoe Lama, Carolina Adura, Wei Xie et al. · Nature Communications · 2019 · 283 citations · Full text

, , +17

Discovery of a Novel, Potent, and Orally Active Nonpeptide Antagonist of the Human Luteinizing Hormone-Releasing Hormone (LHRH) Receptor

Nobuo Cho, Masataka Harada, Toshihiro Imaeda et al. · Journal of Medicinal Chemistry · 1998 · 126 citations · Full text

, , +10

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance

Laura A. Kirkman, Wenhu Zhan, Joseph E. Visone et al. · Proceedings of the National Academy of Sciences · 2018 · 100 citations · Full text

, , +16

Development of a Highly Selective <i>Plasmodium falciparum</i> Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice

Wenhu Zhan, Hao Zhang, John D. Ginn et al. · Angewandte Chemie International Edition · 2021 · 40 citations · Full text

, , +17

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