Karl Welzenbach - Concepedia

Concepedia

Author

Karl Welzenbach

Novartis (Switzerland)

Also Known As

K Welzenbach, K. Welzenbach, Karl A. Welzenbach, Karl Welzenbach, Welzenbach, K., Welzenbach, Karl Albert

34

Publications

2.3K

Citations

16

H-Index

32

Concepts

All Affiliations

Novartis (Switzerland)Novartis Institutes for BioMedical Research Novartis (United States)Centre Hospitalier de l’Université de Montréal Scripps Research Institute

KW

About

Karl Welzenbach is an author at Novartis (Switzerland) specializing in medicine, immunology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	1.8K
2	Immunology	6	6	1.7K
3	Cell Biology	5	5	1.5K
4	Natural Sciences	4	4	479
5	Biochemistry	3	3	223

Karl Welzenbach

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17

Publications

2.3K

Citations

16

H-Index

	Year	Citations
Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site Gabriele Weitz‐Schmidt, Karl Welzenbach, Volker Brinkmann, Nature Medicine InflammationCytokineImmunologyImmune RegulationLeukocyte Function Antigen-1	2001	1K
Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain 1 1Edited by F. E. Cohen Joerg Kallen, Karl Welzenbach, Paul Ramage, Journal of Molecular Biology Lfa-1 InhibitionMolecular PharmacologySignal TransductionMolecular PhysiologyNatural Sciences	1999	256
ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157 Dominik Feuerbach, Patrick Schindler, Carmen Barske, Neuroscience Letters Histidine 157Cleaves Trem2G Protein-coupled ReceptorMain SheddaseImmunology	2017	179
The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation Jean-Pierre Evenou, Jürgen Wagner, Gerhard Zenke, Journal of Pharmacology and Experimental Therapeutics	2009	159
Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer Rainer Albert, Klaus Hinterding, Volker Brinkmann, Journal of Medicinal Chemistry Bioorganic ChemistryBiologically Active SpeciesVivo PhosphorylationImmunologyMedicinal Chemistry	2005	150
Small Molecule Inhibitors Induce Conformational Changes in the I Domain and the I-like Domain of Lymphocyte Function-associated Antigen-1 Karl Welzenbach, Ulrich Hommel, Gabriele Weitz‐Schmidt Journal of Biological Chemistry	2002	80
Improved Lymphocyte Function-associated Antigen-1 (LFA-1) Inhibition by Statin Derivatives Gabriele Weitz‐Schmidt, Karl Welzenbach, Janet Dawson, Journal of Biological Chemistry	2004	68
CD47 fusion protein targets CD172a+ cells in Crohn’s disease and dampens the production of IL-1β and TNF Nobuyasu Baba, Vu Quang Van, Keiko Wakahara, The Journal of Experimental Medicine Chronic Inflammatory DiseasesImmunologyImmune RegulationCd4 T Cell ResponsesInnate Immunity	2013	55
1,4-Diazepane-2-ones as novel inhibitors of LFA-1 Sompong Wattanasin, Rainer Albert, Claus Ehrhardt, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryBiochemistryMedicineNatural SciencesMechanism Of Action	2003	50
1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1 Sompong Wattanasin, Joerg Kallen, Stewart Myers, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyMedicinal ChemistryMedicineMechanism Of ActionPharmacotherapy	2004	44

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