ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157

Dominik Feuerbach, Patrick Schindler, Carmen Barske, +17

Neuroscience Letters

Histidine 157Cleaves Trem2G Protein-coupled ReceptorMain SheddaseImmunology +5

Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo‐66 receptor

V. Pignot, A Hein, Carmen Barske, +6

Journal of Neurochemistry

Molecular BiologyNovel ProteinsCellular PhysiologySocial SciencesNeuroregeneration +18

High LRRK2 Levels Fail to Induce or Exacerbate Neuronal Alpha-Synucleinopathy in Mouse Brain

Martin C. Herzig, Michael Bidinosti, Tatjana Schweizer, +12

PLoS ONE

Neurochemical BiomarkersLrrk2 VariantsSynaptic SignalingSocial SciencesNeuroinflammation +24

Retroviral vectors designed for targeted expression of RNA polymerase III-driven transcripts: a comparative study

Heini Ilves, Carmen Barske, U. Junker, +2

Gene

Viral ReplicationNatural SciencesHuman RetrovirusImmunologyMolecular Biology +10

Comparative Analyses of Intracellularly Expressed Antisense RNAs as Inhibitors of Human Immunodeficiency Virus Type 1 Replication

Gábor Veres, U. Junker, Jenny Baker, +6

Journal of Virology

Inhibitory Activity of Myelin-Associated Glycoprotein on Sensory Neurons Is Largely Independent of NgR1 and NgR2 and Resides within Ig-Like Domains 4 and 5

Verena Wörter, Rüdiger Schweigreiter, Bernd Kinzel, +5

PLoS ONE

NeurotransmissionPeripheral NervesSynaptic SignalingSocial SciencesMyelin-associated Glycoprotein +14

Intracellular Expression of Cellular eIF-5A Mutants Inhibits HIV-1 Replication in Human T Cells: A Feasibility Study

U. Junker, Dorian Bevec, Carmen Barske, +5

Human Gene Therapy

Viral ReplicationImmunologyImmunotherapyIntracellular ExpressionHuman Retrovirus +16

Design and Synthesis of Selective and Potent Orally Active S1P5 Agonists

Henri Mattes, Kumlesh K. Dev, Rochdi Bouhelal, +10

ChemMedChem

Intracellular expression of RNA transcripts complementary to the human immunodeficiency virus type 1 gag gene inhibits viral replication in human CD4+ lymphocytes

Gábor Veres, Sonia Escaich, J Baker, +5

Journal of Virology

Viral ReplicationRna TranscriptsMedicineGag GeneHuman Retrovirus +13

IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling

A. Goepfert, Carmen Barske, Sylvie Lehmann, +8

Cell Reports