Gabriele Weitz‐Schmidt

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

Gabriele Weitz‐Schmidt, Karl Welzenbach, Volker Brinkmann et al. · Nature Medicine · 2001 · 1K citations

Inflammation, Cytokine, Immunology +8

Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain 1 1Edited by F. E. Cohen

Joerg Kallen, Karl Welzenbach, Paul Ramage et al. · Journal of Molecular Biology · 1999 · 256 citations

Lfa-1 Inhibition, Molecular Pharmacology, Signal Transduction +13

The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation

Jean-Pierre Evenou, Jürgen Wagner, Gerhard Zenke et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 159 citations

Small Molecule Integrin Antagonists that Bind to the β2 Subunit I-like Domain and Activate Signals in One Direction and Block Them in the Other

Motomu Shimaoka, Azucena Salas, Wei Yang et al. · Immunity · 2003 · 132 citations · Full text

Signal Transduction, Activate Signals, Block Them +11

Small Molecules as Structural and Functional Mimics of Sialyl Lewis X Tetrasaccharide in Selectin Inhibition:  A Remarkable Enhancement of Inhibition by Additional Negative Charge and/or Hydrophobic Group

Chi‐Huey Wong, Francisco Morı́s-Varas, Shang‐Cheng Hung et al. · Journal of the American Chemical Society · 1997 · 94 citations

Glycobiology, Peptide Science, Chemical Biology +18