Jean-Pierre Evenou

The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation

Jean-Pierre Evenou, Jürgen Wagner, Gerhard Zenke et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 160 citations

Life Sciences, Immunology, Pharmacology +17

Discovery of 3-(1<i>H</i>-Indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a Potent and Selective Inhibitor of Protein Kinase C Isotypes

Jürgen Wagner, Peter Matt, Richard Sedrani et al. · Journal of Medicinal Chemistry · 2009 · 134 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure–Activity Relationship and Pharmacokinetic Studies of Sotrastaurin (AEB071), a Promising Novel Medicine for Prevention of Graft Rejection and Treatment of Psoriasis

Jürgen Wagner, Peter Matt, Bernard Faller et al. · Journal of Medicinal Chemistry · 2011 · 39 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

Rational Design, Synthesis, and X-ray Structure of Selective Noncovalent Thrombin Inhibitors

Jürgen Wagner, Jörg Kallen, Claus Ehrhardt et al. · Journal of Medicinal Chemistry · 1998 · 35 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +15

2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes

Maurice J. van Eis, Jean-Pierre Evenou, Philipp Floersheim et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 33 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +9