Concepedia

An improved method for high-level soluble expression and purification of recombinant amyloid-beta peptide for in vitro studies

Gaurav Chhetri, Tripti Pandey, Ramesh Chinta, Awanish Kumar, Timir Tripathi

Protein Expression and Purification · 2015 · 21 citations · 34 references

DOI

Concepts

References

34

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

Monica Bucciantini, Elisa Giannoni, Fabrizio Chiti et al. · Nature · 2002 · 2.4K citations

, , +17

Natural oligomers of the amyloid-β protein specifically disrupt cognitive function

James Cleary, Dominic M. Walsh, J. Hofmeister et al. · Nature Neuroscience · 2004 · 1.7K citations

, , +16

Evidence that β-Amyloid Protein in Alzheimer's Disease Is Not Derived by Normal Processing

Sangram S. Sisodia, Edward H. Koo, Konrad Beyreuther et al. · Science · 1990 · 891 citations

, , +17

Solubilization and Purification of Enzymatically Active Glutathione S-Transferase (pGEX) Fusion Proteins

John V. Frangioni, Benjamin G. Neel · Analytical Biochemistry · 1993 · 884 citations

, , +12

Solution NMR Studies of the Aβ(1−40) and Aβ(1−42) Peptides Establish that the Met35 Oxidation State Affects the Mechanism of Amyloid Formation

Liming Hou, Haiyan Shao, Yongbo Zhang et al. · Journal of the American Chemical Society · 2004 · 529 citations

, , +17