Concepedia
Biochemical Pharmacology · 2015 · 62 citations · 27 references
InflammationAnti-inflammatoryAutoimmune DiseaseMtorc1-dependent PathwayImmunologyChronic InflammationAutoimmunityUlcerative ColitisAnti-colitis EfficacyMedicineCell BiologyTh17 Cells
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The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5K citations · Full text
Inflammation, Cytokine, Lymphocyte Development +9
The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
Greg M. Delgoffe, Thomas P. Kole, Yan Zheng et al. · Immunity · 2009 · 1.2K citations · Full text
Signal Transduction, Cell Regulation, Signaling Pathway +9
The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
Greg M. Delgoffe, Kristen Pollizzi, Adam T. Waickman et al. · Nature Immunology · 2011 · 1.1K citations · Full text
Kinase Mtor, Signal Transduction, Signaling Pathway +8
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
Mandy J. McGeachy, Yi Chen, Cristina M. Tato et al. · Nature Immunology · 2009 · 1.1K citations · Full text
Terminal Differentiation, Cytokine, Interleukin 23 +10
Distinct Cytokine Patterns Identified from Multiplex Profiles of Murine DSS and TNBS-Induced Colitis
Philip Alex, Nicholas C. Zachos, Thuan T. Nguyen et al. · Inflammatory Bowel Diseases · 2008 · 739 citations · Full text